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Am J Ther 2002;9:472-5.. View abstract. Generally, zinc supplements are safe and well tolerated in adequate amounts. View abstract. Yellowing of the skin in infants (neonatal jaundice). Serum copper and zinc levels in epileptic children with valproate treatment. Research suggests that taking zinc by mouth daily for 90 days does not improve quality of life or symptoms associated with rosacea. View abstract. American Academy of Pediatrics Committee on Drugs. Altern.Ther.Health Med 2006;12(1):34-38. Arsenic poisoning. View abstract. View abstract. Birmingham CL, Goldner EM, Bakan R. Controlled trial of zinc supplementation in anorexia nervosa. Penttila O, Hurme H, Neuvonen PJ. Zinc in ulcerative colitis: a therapeutic trial and report on plasma levels. Z.Gastroenterol. Graham, R. M., James, M. P., and Bennett, S. Low concentration zinc sulphate solution in the management of recurrent herpes simplex infection. A lung disease that makes it harder to breathe (chronic obstructive pulmonary disease or COPD). Cadmium in zinc-containing mineral supplements. The effect of individual components of soy formula and cows' milk formula on zinc bioavailability. However, taking zinc supplements regularly is not recommended. Weismann K, Hoyer H. Serum zinc levels during oral glucocorticoid therapy. Hirt M, Nobel S, Barron E. Zinc nasal gel for the treatment of common cold symptoms: A double-blind, placebo-controlled trial. Zoli A, Altomonte L, Caricchio R, et al. Effects of micronutrient intake on survival in human immunodeficiency virus type 1 infection. View abstract. Drug Saf 1995;12:314-33. View abstract. Int J Food Sci Nutr 1995;46:53-63. Belmont, CA: Wadsworth, 1998. 1991;19(1):29-31. View abstract. (check all that apply), What factors are most important to you? Am J Clin Nutr 1999;69:509-15.. View abstract. Grattan, B. J. and Freake, H. C. Zinc and cancer: implications for LIV-1 in breast cancer. Taking zinc along with the drug prazosin does not seem to improve the ability to urinate or quality of life compared to taking prazosin alone in men with prostate swelling. Nowak, G., Siwek, M., Dudek, D., Zieba, A., and Pilc, A. Lassi, Z. S., Haider, B. Macknin ML, Piedmonte M, Calendine C, et al. View abstract. Hunt JR. Moving toward a plant-based diet; are iron and zinc at risk? Zinc side effects can become potentially serious if you take doses from 150 to 450 mg a day. Also, zinc does not appear to prevent infant death or maternal wasting in pregnant women with HIV. View abstract. B., Larson, C. P., Khan, A. M., and Saha, U. R. Initiation of zinc treatment for acute childhood diarrhoea and risk for vomiting or regurgitation: a randomized, double-blind, placebo-controlled trial. Nutrition and the pill. J Androl 2000;21:53-7. Lancet 7-20-1985;2(8447):157. Medical Information Department, Wyeth Pharmaceuticals Inc., Philadelphia, PA. February 24, 2005. Effect of zinc supplementation on malaria and other causes of morbidity in west African children: randomised double blind placebo controlled trial. Clin Nutr. J Nutr 2000;130:1512S-5S. Hurd RW, Wilder BJ, Van Rinsvelt HA. Serum zinc in acne vulgaris. Effects of oral ethinyl oestradiol and norethisterone on plasma copper and zinc complexes in post-menopausal women. Br.J Nutr 2006;95(5):963-967. Am.J Epidemiol. View abstract. View abstract. Two randomized controlled trials of zinc gluconate lozenge therapy of experimentally induced rhinovirus colds. Walker, C. L., Bhutta, Z. A. Topical zinc sulphate solution for treatment of viral warts. Chia SE, Ong CN, Chua LH, et al. View abstract. Although some conflicting results exist, most research shows that taking lozenges containing zinc gluconate or zinc acetate by mouth helps reduce the duration of a cold in adults. Int.J.Immunopharmacol. Sheikh, A., Shamsuzzaman, S., Ahmad, S. M., Nasrin, D., Nahar, S., Alam, M. M., Al, Tarique A., Begum, Y. 2012 Mar;30(1):22-6. Br.Med.J. Int Urol Nephrol 1999;31:401-8. Methylphenidate for children and adolescents with autism spectrum disorder. View abstract. Chem Senses 2000;25:659. Laryngoscope 2006;116:217-20. Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. Applying zinc oxide paste also seems to improve the healing of diaper rash. Am J Clin Nutr 1998;68:442S-6S. View abstract. Dermatology Res Pract. Malaria. Taking zinc by mouth reduces the duration and severity of diarrhea in children who are undernourished or zinc deficient. Sazawal, S., Jalla, S., Mazumder, S., Sinha, A., Black, R. E., and Bhan, M. K. Effect of zinc supplementation on cell-mediated immunity and lymphocyte subsets in preschool children. Henkin RI, Martin BM, Agarwal RP. J Nutr 2010;140(9):1677-1682. Lu, H., Cai, L., Mu, L. N., Lu, Q. Y., Zhao, J., Cui, Y., Sul, J. H., Zhou, X. F., Ding, B. G., Elashoff, R. M., Marshall, J., Yu, S. Z., Jiang, Q. W., and Zhang, Z. F. Dietary mineral and trace element intake and squamous cell carcinoma of the esophagus in a Chinese population. View abstract. J Neurol Sci 1987;77:137-46. Zinc supplementation is associated with improved neurologic recovery rate and visceral protein levels of patients with severe closed head injury. 2005;9(12):1378-1384. Yunice AA, Czerwinski AW, Lindeman RD. 1984;38:119-128. View abstract. Digestion 1992;51:18-26. Continuous desferrioxamine infusion by an infusor in thalassemia major. Taking zinc by mouth or giving zinc intravenously (by IV) helps to restore zinc levels in people who are zinc deficient. Crofton RW, Gvozdanovic D, Gvozdanovic S, et al. BMC.Med 2009;7:22. View abstract. View abstract. J Health Popul.Nutr 2008;26(3):356-365. The impact of zinc supplementation on Schistosoma mansoni reinfection rate and intensities: a randomized, controlled trial among rural Zimbabwean schoolchildren. Arch Ophthalmol 1988;106:192-8. Colon cancer, rectal cancer. View abstract. View abstract. View abstract. View abstract. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. View abstract. View abstract. B., Dhande, L. A., and Rawat, M. S. Therapeutic evaluation of zinc and copper supplementation in acute diarrhea in children: double blind randomized trial. 1982;41(5):456-457. Results of a randomised controlled trial. Biol Trace Elem Res. View abstract. Osendarp, S. J., Santosham, M., Black, R. E., Wahed, M. A., van Raaij, J. M., and Fuchs, G. J. Akhondzadeh S, Mohammadi MR, Khademi M. Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children :a double blind and randomized trial. 2016;115(5):807-16. Zinc sulphate for acute bronchiolitis: A double-blind Effects of zinc treatment in patients with recurrent aphthous stomatitis. View abstract. View abstract. van de Wal Y, van der Sluys Veer A, Verspaget HW, et al. Optimal administration schedule of cisplatin for bladder tumor with minimal induction of metallothionein. Am J Hematol. J Int Med Res 1992;20:234-6. It is usually quite easy for us to identify and avoid such substances, … Wester PO. View abstract. Early research suggests that taking zinc reduces the healing time after surgery used to treat an abnormal skin growth located at the tailbone (pilonidal surgery). 1970;172(6):1048-1050. J Dermatolog.Treat. View abstract. For a dose of 50mg elemental zinc, take 385 mg zinc gluconate. 2017;15(1):24-28. View abstract. Valberg LS, Flanagan PR, Chamberlain MJ. Biol Psychiatry. Castillo-Duran, C., Rodriguez, A., Venegas, G., Alvarez, P., and Icaza, G. Zinc supplementation and growth of infants born small for gestational age. Henkin RI, Schecter PJ, Friedewald WT, et al. Warts. Mulder TP, van der Sluys Veer A, Verspaget HW, et al. Influence of vegetable protein sources on trace element and mineral bioavailability. J Gastroenterol Hepatol 1994;9:472-7. Am J Clin Nutr 1975;28:377-84. View abstract. View abstract. View abstract. Comp Immunol.Microbiol.Infect.Dis. Najafabadi MM, Faghihi G, Emami A, Monghad M, Moeenzadeh F, Sharif N, Davarpanah Jazi AH. Zinc side effects can become potentially serious if you take doses from 150 to 450 mg a day. View abstract. View abstract. O'Brien KO, Zavaleta N, Caulfield LE, et al. 2012 Jul;15(7):413-7. Acute adverse effects of high zinc intake include nausea, vomiting, loss of appetite, abdominal cramps, diarrhea, and headaches [ 2 ]. Medicine (Baltimore) 2019;98(10):e14637. Floersheim, G. L. and Lais, E. [Lack of effect of oral zinc sulfate on wound healing in leg ulcer]. View abstract. View abstract. Yoshida, S., Endo, S., and Tomita, H. A double-blind study of the therapeutic efficacy of zinc gluconate on taste disorder. Oral zinc sulphate in the treatment of acute cutaneous leishmaniasis. Paaske PB, Pedersen CB, Kjems G, Sam IL. View abstract. View abstract. Malla L, Perera-Salazar R, Akech S, et al. View abstract. Alzheimer disease. Brewer GJ, Yuzbasiyan-Gurkan V, Johnson V, et al. View abstract. The incidence of optic neuropathy in 84 patients treated with ethambutol. National Institutes of Health "Dietary supplement fact sheet: zinc. View abstract. Serum copper, zinc, selenium, glutathione peroxidase and superoxide dismutase levels in epileptic children before and after 1 year of sodium valproate and carbamazepine therapy. View abstract. Eur J Clin Nutr 1995;49:282-8. View abstract. However, zinc gluconate lozenges might help prevent colds in children and adolescents. View abstract. The American Pharmaceutical Association Practical Guide to Natural Medicines. Sazawal, S., Black, R. E., Jalla, S., Mazumdar, S., Sinha, A., and Bhan, M. K. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial. Dermatology 2004;209(1):46-49. 2012 Feb;105(2):39-40, 42. Short term effects of zinc toxicity include nausea, vomiting, diarrhea, headaches, stomach cramps, loss of appetite, and irritability [ 12 ]. Wound Repair Regen. View abstract. 2008;26(1):97-102. Effect of oral zinc supplementation on metallothionein and superoxide dismutase concentrations in patients with inflammatory bowel disease. Am J Clin Nutr 2005;82(3):605-610. Serjeant, G. R., Galloway, R. E., and Gueri, M. C. Oral zinc sulphate in sickle-cell ulcers. J Toxicol Clin Toxicol 1999;37:279-92. Rapid serum zinc depletion associated with corticosteroid therapy. Brain Res 1999;823:88-95. Am J Clin Nutr 2000;71:956-61. Sheng, X. Y., Hambidge, K. M., Krebs, N. F., Lei, S., Westcott, J. E., and Miller, L. V. Dysprosium as a nonabsorbable fecal marker in studies of zinc homeostasis. Pierard-Franchimont C, Goffin V, Visser JN, et al. Indian J Pediatr. Wilkinson EA, Hawke CI. Otol.Neurotol. Hurrell RF. Complement Ther Clin Pract 2009;15(2):91-95. West Indian Med J 1975;24(1):26-29. View abstract. DeCook CA, Hirsch AR. Bianchi GP, Marchesini G, Brizi M, et al. Control of gingivitis and calculus by a dentifrice containing a zinc salt and triclosan. View abstract. Improvement of uremic neuropathy and hypogeusia by dialysate zinc supplementation: a double-blind study. Curr Ther Res 1998;59:595-607. Effect of zinc therapy on neutrophil chemotaxis in psoriasis. Some side effects may not be reported. thanks. Attention deficit-hyperactivity disorder (ADHD). Patel, A., Dibley, M. J., Mamtani, M., Badhoniya, N., and Kulkarni, H. Zinc and copper supplementation in acute diarrhea in children: a double-blind randomized controlled trial. 2013 Oct;98(4):960-71. Expanded activity and utility of the new fluoroquinolones: a review. Modern Nutrition in Health and Disease. Demetree, J. W., Safer, L. F., and Artis, W. M. The effect of zinc on the sebum secretion rate. B., and Campa, A. Randomized, controlled clinical trial of zinc supplementation to prevent immunological failure in HIV-infected adults. View abstract. Interactions with the absorption of tetracyclines. Prasad AS, Fitzgerald JT, Bao B, et al. Chevalier, C. A., Liepa, G., Murphy, M. D., Suneson, J., Vanbeber, A. D., Gorman, M. A., and Cochran, C. The effects of zinc supplementation on serum zinc and cholesterol concentrations in hemodialysis patients. Walker, C. L. and Black, R. E. Zinc for the treatment of diarrhoea: effect on diarrhoea morbidity, mortality and incidence of future episodes. Clin Infect.Dis. Zinc is important for your sense of taste. Comparison of oral treatment with zinc sulphate and placebo in acne vulgaris. Arch Iranian Med 2008;11:392-6. Taking zinc might prevent these seizures in children who already experienced one. Newsome DA, Swartz M, Leone NC, et al. 1986;9(2-3):241-252. Zinc 50 mg , 100 Caplets Natures Bounty Zinc 50 mg 100 is rated 5.0 out of 5 by 1 . Persistent anosmia following zinc sulfate nasal spraying. Nutrients. View abstract. View abstract. View abstract. Am J Med Sci 1976;272:285-99. Zinc is a trace element that is essential for regulating the immune system. 2005;24(6):979-987. 2012 Mar;73(3):422-7. Rosado, J. L., Lopez, P., Munoz, E., Martinez, H., and Allen, L. H. Zinc supplementation reduced morbidity, but neither zinc nor iron supplementation affected growth or body composition of Mexican preschoolers. Grimwood, K. and Forbes, D. A. 2001;90(4):376-380. View abstract. Intensive Care Med 2000;26:s413-21. Metabolism 1984;33:491-501. Arch Iran Med. Allain P, Mauras Y, Premel-Cabic A, et al. Meynadier J. Efficacy and safety study of two zinc gluconate regimens in the treatment of inflammatory acne. Am J Clin Nutr 1984;39:535-9. The longer you “overdose” on zinc, the worse your side effects will be. Exp Clin Endocrinol Diabetes. van Leeuwen R, Boekhoorn S, Vingerling JR, et al. View abstract. The value of methods to determine zinc deficiency in patients with Crohn's disease. Koletzko B, Bretschneider A, Bremer HJ. Neuvonen PJ. Prasad AS. Fertil Steril 2002;77:491-8.. View abstract. Bao, B., Prasad, A. S., Beck, F. W., Fitzgerald, J. T., Snell, D., Bao, G. W., Singh, T., and Cardozo, L. J. Zinc decreases C-reactive protein, lipid peroxidation, and inflammatory cytokines in elderly subjects: a potential implication of zinc as an atheroprotective agent. Am J Clin Nutr 1984;40:1064-70. 1997;34(7):589-597. Early research has linked low intake of zinc with an increased risk of esophageal cancer. 6-15-2010;50(12):1653-1660. J Trace Elem Med Biol 1997;11:65-70. View abstract. Nutr Cancer 2006;55(1):63-70. Antimicrob Agents Chemother 1989;33:1841-4. Dooren JC. Lancet 3-17-2007;369(9565):927-934. View abstract. Just want to point out that, in most cases, we really don't need to worry about exceeding the 40 mg daily UL of elemental Zinc because there's way less than 40 mg of elemental Zinc in a 50 mg tablet of Zinc gluconate if we take one per day.. For example, there's only 7 mg of elemental Zinc (14.3%) in 50 mg of Zinc … Metabolism 1998;47(7):792-798. Age-Related Macular Degeneration PPP - Updated 2015. www.aao.org/preferred-practice-pattern/age-related-macular-degeneration-ppp-2015. Factors affecting zinc homeostasis. II. Skin infection caused by Leishmania parasites (Leishmania lesions). Effect of micronutrient supplementation on infection in institutionalized elderly subjects: a controlled trial. Acta Med Scand 1980;208:209-12. Sweeney JD, Ziegler P, Pruet C, Spaulding MB. View abstract. But zinc doesn't seem to improve attention span. View abstract. View abstract. View abstract. Call your doctor for medical View abstract. 2012 Nov 1;3(6):772-82. Arch Neurol. Thus, zinc supplements are of interest for people with ADHD. Early research suggests that taking zinc reduces cholesterol but not triglycerides in people with clogged arteries. Am.J.Trop.Med.Hyg. The recommended daily allowance (RDA) of elemental zinc for adult women and men is 8 mg and 11 mg per day, respectively. Duchateau, J., Delepesse, G., Vrijens, R., and Collet, H. Beneficial effects of oral zinc supplementation on the immune response of old people. Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. J Clin Microbiol 2000;38:1758-62. Moran, J., Newcombe, R. G., Wright, P., Haywood, J., Marlow, I., and Addy, M. A study into the plaque-inhibitory activity of experimental toothpaste formulations containing antimicrobial agents. Am J Clin Nutr 2002;76(6):1401-1408. The World Health Organization and UNICEF now recommend short-term zinc supplementation (20 mg of zinc per day, or 10 mg for infants under 6 months, for 10–14 days) to treat acute childhood diarrhea . Z. View abstract. Dark skin patches on the face (melasma). Zinc supplementation might potentiate the effect of vitamin A in restoring night vision in pregnant Nepalese women. Frommer DJ. Taste loss associated with oral captopril treatment. Office of Dietary Supplements. July 14, 2016. Toren P, Eldar S, Sela BA, et al. View abstract. Mossad SB. Shils ME, Olson JA, Shike M, Ross AC, eds. Antimicrob Agents Chemother. 1997;8(2 Spec No):62-66. View abstract. Dutta, P., Mitra, U., Datta, A., Niyogi, S. K., Dutta, S., Manna, B., Basak, M., Mahapatra, T. S., and Bhattacharya, S. K. Impact of zinc supplementation in malnourished children with acute watery diarrhoea. Taking zinc by mouth does not seem to help treat rheumatoid arthritis. Huang X, Cuajungco MP, Atwood CS, et al. Clin Chem 1996;42:1938-42. View abstract. Pediatrics 2002;109(6):e86. Effects of oral contraceptive agents on trace element metabolism - a review. Tang, Y., Yang, Q., Lu, J., Zhang, X., Suen, D., Tan, Y., Jin, L., Xiao, J., Xie, R., Rane, M., Li, X., and Cai, L. Zinc supplementation partially prevents renal pathological changes in diabetic rats. View abstract. View abstract. Aggarwal R, Sentz J, Miller MA. 3. View abstract. View abstract. Palomo F, Wantland L, Sanchez A, Volpe AR, McCool J, DeVizio W. The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: a six month clinical study. Aust.N.Z.J Obstet.Gynaecol. Treatment response to antioxidants and zinc based on CFH and ARMS2 genetic risk allele number in the Age-Related Eye Disease Study. Leprosy. Scholl, T. O., Hediger, M. L., Schall, J. I., Fischer, R. L., and Khoo, C. S. Low zinc intake during pregnancy: its association with preterm and very preterm delivery. Pregnancy complications in women with HIV/AIDS. But zinc supplementation doesn't seem to reduce the risk for stillbirths, miscarriage, or infant deaths. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. Br J Nutr 1995;74:417-25.. View abstract. View abstract. Veverka, D. V., Wilson, C., Martinez, M. A., Wenger, R., and Tamosuinas, A. Arch Dermatol 1977;113:31-6. Foot ulcers heal faster than conventional treatments Kwiatkowski JL, Wu QC Chelation by deferoxamine in zinc 50 mg side effects cell:. The second eye in age-related macular degeneration and the common cold in children severe. 385 mg zinc content on a candy, or perfused mouse intestine nausea/vomiting, abdominal pain and diarrhea B. anosmia! Do women using oral contraceptive use: a meta-analysis well tolerated in adequate amounts JL, Wu Y from products. Small for gestational age reduces mortality: a double-blind trial of intralesionally-administered zinc solution! 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